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Search Results for " caspase cascade "

11

Compounds

Cat No. Product Name Synonyms Targets
T7982 3,6-Dihydroxyflavone Others
3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.
T0432 Diclofenac diethylamine Apoptosis , COX
Diclofenac Diethylamine, a non-selective COX inhibitor, is utilized as a nonsteroidal anti-inflammatory drug (NSAID).
T0196 Diclofenac Diclofenacum,Voltaren Apoptosis , COX
Diclofenac (Diclofenacum) is a nonsteroidal benzeneacetic acid derivative with anti-inflammatory activity. Diclofenac binds and chelates both isoforms of cyclooxygenase (COX-1 and-2), thereby blocking the conversion of a...
T6470 Diclofenac Potassium CGP-45840B,Cataflam,Voltfast Apoptosis , Others , COX
Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.
T1555 Diclofenac sodium GP 45840 Apoptosis , COX
Diclofenac sodium (GP 45840) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
T24784 SF5 SF-5,SF 5 Apoptosis
SF5 is an inhibitor of the apoptosis pathway. Which is through the JNK-p53-caspase apoptotic cascade.
T69500 YO-2
YO-2 is a selective plasmin inhibitor. YO-2 induces thymocyte apoptosis via activation of caspase cascade.
T36331 Z-AEVD-FMK Z-AEVD-FMK,Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone
Z-AEVD-FMK is an irreversible inhibitor of caspase-10 and related caspases.[1] At 10 µM, it can prevent the initiation of Fas signaling by caspase-10 in Jurkat T lymphoma cells, preventing Bid cleavage into its activ...
T27305 Fascaplysin chloride NSC622398,NSC 622398,Fascaplysin,NSC-622398
Fascaplysin is a cyclin D kinase 4/ cyclin D1 inhibitor (IC50 = 0.35 μM). Fascaplysin induces caspase mediated crosstalk between autophagy and apoptosis through the inhibition of PI3K/AKT/mTOR signaling cascade in human ...
T74844 Antiproliferative agent-23
Antiproliferative agent-23, a microtubule-destabilizing agent (MDA), disrupts the tubulin-microtubule system, leading to apoptosis through a mitochondrion-dependent pathway. This involves downregulation of Bcl-2 protein,...
T36954 Nemorosone
Nemorosone is a polycyclic polyprenylated acylphloroglucinol (PPAP) originally isolated from C. rosea that has antiproliferative properties.1 Nemorosone inhibits growth of NB69, Kelly, SK-N-AS, and LAN-1 neuroblastoma ce...
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